Chemical Biology of Natural Products: Target ID and Activity Control - Scientific Research on Innovative Areas, a MEXT Grant-in-Aid Project FY2011-2015

International Confrence 2012

International Confrence 2012

A01A02A03

【A01】

Hiroshi Handa, A01 Group Leader
Professor, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
  1. Hiroshi Handa, “Expansion from chemical target identification to drug discovery”, The 1st International Symposium oh Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto (Oct.-Nov., 2012).
Ryuichi Okamoto
Associate Professor, Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University
  1. Tatsuro Murano, Ryuichi Okamoto, Hiromichi Shimizu, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Hes1 promotes IL-22-mediated epithelial regeneration through enhancement of STAT3-dependent transcription in human intestinal epithelial cells” DDW2012, SanDiego, USA (May, 2012).
  2. Yoshihito Kano, Kiichiro Tsuchiya, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe, “The acquisition of cancer stemness in colon cancer by the Atoh1 protein stabilization” DDW2012, SanDiego, USA (May, 2012).
  3. Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Notch signaling regulates expression of Gelsolin superfamily genes, gelsolin and Scinderlin, and promotes re-assembly of actin cytoskelton in human intestinal epithelial cells” DDW2012, SanDiego, USA (May, 2012).
  4. Tomohiro Mizutani, Kiichiro Tsuchiya, Ryuichi Okamoto, Tetsuya Nakamura, MamoruWatanabe, “Real-time analysis of p-glycoprotein-mediated drug transport across primary intestinal epithelial cells three-dimensionally cultured in vitro” DDW2012, SanDiego, USA (May, 2012).
  5. Kiichiro Tsuchiya, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe, “Flagellinresponse via TLR5 on basolateral membrane of primary intestinal epithelial cells is regulated by Notch signaling” DDW2012, SanDiego, USA (May, 2012).
  6. Yasuhiro Nemoto, Takanori Kanai, Kiichiro Tsuchiya, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe, “Colitogenic effector memory CD4+ T cells develop TH1/TH17 mediated interstitial pneumonia independent to intestinal bacterial antigens” DDW2012, SanDiego, USA (May, 2012).
  7. Go Ito, Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/ Cl- channel, in human intestinal epithelial cells” UEGW2012, Amsterdam, Netherlands (Nov, 2012).
  8. Ryuichi Okamoto, Go Ito, Tatsuro Murano, Hiromichi Shimizu, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Notch signaling and TNF-alpha synergistically up-regulate OLFM4 expression in human intestinal epithelial cells” UEGW2012, Amsterdam, Netherlands (Nov, 2012).
  9. Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Satoru Fujii, Kiichiro Tsuchiya,Tetsuya Nakamura, Mamoru Watanabe, “Hes1 promotes IL-22-mediated epithelial regeneration through enhancement of STAT3-dependent transcription in human intestinal epithelial cells” Asian IBD Symposium 2012, Seoul, Korea (Oct, 2012).
  10. Hiromichi Shimizu, Ryuichi Okamoto, Tatsuro Murano, Go Ito, Satoru Fujii, Morio-Akiyama Junko, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Identification of Notch ligand expressing cells in normal and inflamed intestinal mucosa” Asian IBD Symposium 2012, Seoul, Korea (Oct, 2012).
  11. Ryuichi Okamoto, Junko Akiyama, Hiromichi Shimizu, Tatsuro Murano, Go Ito, KiichiroTsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Notch-Hes1 pathway and TNF- synergistically up-regulates OLFM4 expression in the inflamed mucosa of the human intestine” 6th Korea-Japan IBD Symposium, Tokyo, Japan (Jan, 2012).
  12. Tatsuro Murano, Ryuichi Okamoto, Hiromichi Shimizu, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, “Hes1 promotes IL-22-mediated epithelial regeneration through enhancement of STAT3-dependent transcription in human intestinal epithelial cells” 6th Korea-Japan IBD Symposium, Tokyo, Japan (Jan, 2012).
Hajime Watanabe
Professor, Graduate School of Engineering, Osaka University
Motomasa Kobayashi
Professor, Graduate School of Pharmaceutical Sciences, Osaka University
Co-Researcher:Masayoshi Arai, Naoyuki Kotoku.
  1. Yoshi Yamano, Masayoshi Arai, Motomasa Kobayashi, “Search for anti-dormant mycobacterial substances from marine sponges and analysis of their action-mechanism.”, The 7th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists, Kyoto, Japan (May, 2012).
  2. Motomasa Kobayashi, “Medicinal Seeds for Cancer Chemotherapy from Marine Organisms.”, 7th U.S.-Japan Seminar on Marine Natural Products, Okinawa, Japan (Dec, 2012).
Kenichi Nishiyama
Professor, Cryobiofrontier Research Center, Faculty of Agriculture, Iwate University
  1. Ken-ichi Nishiyama, Masahide Maeda, Kayo Yanagisawa, Ryohei Nagase, Hajime Komura,Takashi Iwashita, Shoichi Kusumoto, Hajime Tokuda and Keiko Shimamoto, “MPIase as a glycolipozyme essential for membrane protein integration”, Gordon Research Conference on Bacterial Cell Surface, Wset Dover, VT, USA (Jun, 2012)
  2. Michael Moser, Shushi Nagamori, Maria Huber, Hajime Tokuda, Ken-ichi Nishiyama, “MPIase, a novel glycolipozyme, is essential for topology inversion of SecG” The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto (Oct, 2012)
Shin Hamamoto
Assistant Professor, Graduate School of Engineering, Tohoku University
  1. Shin Hamamoto, Yasuo Mori, Isamu Yabe, Nobuyuki Uozumi, Characterization of YVC1Channel in Yeast Vacuolar Membrane, 2012 International Ion Channel Conference, Jeju, Korea (Aug 2012)
Kohji Fukunaga
Professor,Graduate School of Pharmaceutical Sciences, Tohoku University
  1. Kohji Fukunaga, “The mitochondrial Ca2+ transport and ATP production though sigma-1receptor in heart.”, (No. 4) in Basic Cardiovascular Sciences 2012 Scientific Sessions, New Orleans, Louisiana, USA (July, 2012).
  2. Kohji Fukunaga, “Novel Alzheimer’s therapeutics, ST101 enhances acetylcholine release through T-type voltage-gated calcium channel” (P2-379) in Alzheimer’s Association of International Conference, Vancouver, Canada (July, 2012).
  3. Kohji Fukunaga, “Drug Development of Novel Cognitive Enhancer for Alzheimer DiseaseTherapy” (Lecture 12) in New Perspectives in the Neuroscience of Psychiatric and Neurological Disorders, Soul, Korea (Feb, 2012).
Kazuhisa Sekimizu
Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
  1. Kazuhisa Sekimizu, Hiroshi Hamamoto, “Mechanistic Analysis of Novel Antibiotics Kaikosins”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto, Japan (Oct. 2012).
  2. Su Jie, Hiroshi Hamamoto, Kazuhisa Sekimizu, “Purification of a serum factor enhancing Kaikosin E activity against Staphylococcus aureus”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto, Japan (Oct. 2012).
Maiko Okada
Assistant Professor, Department of Translational Oncology / St.Marianna University School of Medicine.
  1. Maiko Okada, “A mitotic estrogen receptor alpha complex acts as an E3 ubiquitin ligase”, The 35 th Naito conference on “ The Ubiquitin-Proteasome System: From Basic Mechanisms to Pathophysiological Roles”
Nobuaki Matsumori
Associate Professor, Graduate School of Science, Osaka Univeristy
  1. Nobuaki Matsumori, “J-Based Configuration Analysis method: basic concepts and applications”, Small Molecule NMR Conference (SMASH), Providence, Rhode Island (Sep, 2012). (Invited)
  2. Nobuaki Matsumori, “Membrane-bound structures of natural products revealed by isotropic bicelles”, 17th Malaysian Chemical Congress (17MCC), Kuala Lumpur, Malaysia (Oct, 2012). (Invited)
  3. Nobuaki Matsumori, “J-Based Configuration Analysis method: basic concepts and applications”, Cambodian Malaysian Chemical Congress (CMCC), Siem Riap, Cambodia (OCt, 2012). (Invited)
Toshiaki Okuno
Associate Professor, Juntendo University School of Medicine
  1. Okuno T., Natsunobu T., Yokomizo T.Two distinct pathways for biosynthesis of 12-HHT, a ligand for BLT2 receptor.12th Biennial International Endotoxin & Innate Immunity Society (IEIIS) Meeting, 2012/10/23-26, 2012, Tokyo
Akihiro Sugawara
Assistant Professor,
Kitasato Institute for Life Sciences &Graduate School of Infection Control Sciences, Kitasato University
  1. Akihiro Sugawara, Akito Sueki, Tomoyasu Hirose, Hideaki Shima, Kiyoko S.Akagawa, Satoshi Omura, Toshiaki Sunazuka, Novel 12-membered non-antibiotic macrolides;EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. 2nd Mahidol University–Kitasato University Joint Symposium~Natural Products and Biodiversity (Nov, 2012), Oral resentation(Invited)
  2. Akihiro Sugawara “Identification of a target protein of novel macrolides withanti-inflammatory activity and che-mical screening aimed at discovery of novel natural products using ferrite-glycidyl methacrylate beads”The 1st International Symposium oh Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto (Oct, 2012) Poster.
Shuichi Sakamoto
Senior Researcher, Institute of Microbial Chemistry
  1. S. Sakamoto, M. Kawada, H. Inoue, S. Ohba, I. Usami, A. Nomoto, “Development of a novel orthotopic transplantation model of human small cell lung cancer metastasis”, in 14th International Biennial Conference on Metastasis Research 2012, Brisbane, Australia (Sep. 2012)
Soichi Kojima
Unit Leader, RIKEN Center for Life Science Technology
  1. Soichi Kojima, “Acyclic retinoid induces tumor-selective cell death in hepatocarcinoma tumor stem cells and inhibits angiogenesis via suppressing phosphorylation” in 2012 FASB Summer Conference on Retinoids, Snowmass, CO, USA, (June 2012). Invited
  2. Soichi Kojima, “ Essential role of transglutaminase 2 in tumor angiogenesis” in 2nd Gordon Research Conference on Transglutaminases in Human Disease Processes, Davidson, NC, USA, (July 2012). Invited
Koichi Watashi
Senior Researcher, National Institute of Infectious Diseases
  1. K. Watashi, N. Uchida, R. Suzuki, H. Aizaki, T. Wakita, “Phospholipase D is a cellular regulator during hepatitis C virus egress and a possible target for antiviral strategy”, 10th Single Topic Conference, Tokyo, Japan (Nov, 2012).
  2. H.H. Aly, K. Watashi, N. Watanabe, M. Mizokami, T. Kato, T. Wakita, “Construction of hepatitis C virus genotype 4a clone”, 19th International Symposium on hepatitis C virus and related viruses, Venice, Italy (Oct, 2012).
  3. R. Suzuki, M. Matsuda, K. Watashi, H. Aizaki, Y. Matsuura, T. Suzuki, T. Wakita, “An alternative endocytosis pathway for the protective entry of hepatitis C virus”, 19th International Symposium on hepatitis C virus and related viruses, Venice, Italy (Oct, 2012).
  4. Y. Matsumoto, N. Watanabe, K. Watashi, R. Suzuki, T. Matsuura, T. Suzuki, T. Miyamura, K. Wake, T. Wakita, H. Aizaki, “Antiviral activity of glycyrrhizin against hepatitis C virus in vitro”, 19th International Symposium on hepatitis C virus and related viruses, Venice, Italy (Oct, 2012).
  5. K. Watashi, N. Uchida, M. Saeed, R. Suzuki, H. Aizaki, T. Wakita, “Characterization of anti-HCV release inhibitors targeting phospholipase D”, 19th International Symposium on hepatitis C virus and related viruses, Venice, Italy (Oct, 2012).
  6. N. Uchida, K. Watashi, R. Suzuki, H. Aizaki, J. Chiba, T. Wakita, “Phospholipase D regulates membrane trafficking during hepatitis C virus egress”, 19th International Symposium on hepatitis C virus and related viruses, Venice, Italy (Oct, 2012).
  7. K. Watashi, M. Iwamoto, N. Uchida, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita,“Development of cell clones for analyzing anti-hepatitis B virus compounds”, 2012 International Meeting on Molecular Biology of Hepatitis B viruses, Oxford, England (Sep, 2012).
  8. K. Watashi, N. Uchida, T. Daito, T. Kiyohara, R. Suzuki, H. Aizaki, T. Wakita, “Interleukin-1 and tumor necrosis factor-alpha suppressed hepatitis B virus infection through NF-kappaB signaling pathway”, 2012 International Meeting on Molecular Biology of Hepatitis B viruses, Oxford, England (Sep, 2012).
  9. S. Shimura, M. Ishima, I. Ota, E. Tsutsui, S. kamisuki, H. Murata, T. Yamazaki, T. Suzuki, K. Kuramochi, T. Takeuchi, K. Watashi, S. Kobayashi, F. Sugawara, “Synthetic studies of MA026, a novel antiviral lipocyclodepsipeptide”, International Congress on Natural Products Research 2012, New York, USA (July, 2012).

【A02】

Kazuhiro Irie, A02 Group Leader
Professor, Graduate School of Agriculture, Kyoto Universiy
  1. Irie, K., “Structure-activity studies of the simplified analogue of aplysiatoxin with anti-proliferative activity like bryostatins”, in 1st International Symposium on Innovative Areas “Chemical Biology of Natural Products”, Kyoto, Japan (Oct, 2012) (Invited Lecture).
  2. Kikumori, M., Yanagita, R. C., Tokuda, H., Suzuki, N., Nagai, H., Suenaga, K., Irie, K., “Structure–activity studies on the spiroketal moiety of aplog-1, a simplified analogue of debromoaplysiatoxin with anti-proliferative activities”, in The 12th International Kyoto Conference on New Aspects of Organic Chemistry, Kyoto, Japan (Nov, 2012) (Poster Presentation).
Masaya Imoto
Professor,Faculty of Science and Technology, Keio University
Co-Researcher: Etsu Tashiro
  1. Masaya Imoto. “Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration” Riken-Max Planck Joint Research Center“Kick Off Symposium”. Dortmund, Germany (Mar. 2012)
  2. Masaya Imoto. “Drug Seed Generation from Natural Products” 3rd MEXT-ARDA PROJECT Concluding Joint Seminar and JSPS-NRCT ASIAN CORE PROGRAM Joint Seminar. Bangkok, Thailand (Aug. 2012)
  3. Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, Masaya Imoto. “A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds” EMBO Conference (European Molecular Biology Organization. Girona, Spain (Oct 2012)
  4. Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto. “Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology” FOSBE 2012. Tsuruoka (Oct. 2012)
  5. Sigeyuki. Magi, E.Tashiro, M. Imoto. “Involvement of Cysteinyl Leukotriene Receptor 1 (CysLT1) in Second Wave Rac1 Activation in the Process of EGF-induced Cell Migration” 24th EORTC-AACR-NCI-International Conference, Dublin Ireland (Nov. 2012)
Shigeki Matsunaga
Professor,Graduate School of Agricultural and Life Sciences, The University of Tokyo
  1. Suzuki, M, Sun, Y, Akiyama, T, Takada, K, Okada, S, Matsunaga, S, “Biologically active metabolites from sponges and microbes”, The 9th Asia-Pacific Marine Biotechnology Conference, Kochi City Plaza, Kochi (Jul, 2012).
  2. Matsunaga, S, “Bioactive ligands from marine organisms”, 2012 International Symposium on Natural Product and Drug Discovery and Pharmaceutical Education, Sunchon National University, Sunchon, Korea (Oct, 2012).
  3. Matsunaga, S, “Bioactive ligands from marine organisms”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto Century Hotel, Kyoto (Nov, 2012).
  4. Matsunaga, S, “Bioactive ligands from marine organisms”, The 7th International conference on cutting-edge organic Chemistry in Asia, Nanyang Technological University, Singapore (Dec, 2012).
Masami Ishibashi
Professor, Graduate School of Pharmaceutical Sciences, Chiba University
Co-Researcher:Midori Arai, Kazufumi Toume.
  1. M. A. Arai, “Search for naturally occurring neural stem cells activators that modulate bHLH transcriptional factors”, 7th International Conference on Cutting-Edge Organic Chemistry in Asia, Singapore (Dec, 2012)
  2. M. Ishibashi, “Search for bioactive small molecules with Hh signal inhibitory activity from natural resources” Hedgehog 2012, Singapore (Mar, 2012)
  3. M. A. Arai, “Search for cancer cells signaling inhibitors and neural stem cells activators based on natural products”, Asian Chemical Biology Initiative 2012 Hanoi Meeting; Hanoi (Feb, 2012)
Tetsuro Shinada
Professor, Graduate School of Science, Osaka City University
Co-Researcher: Yasufumi Ohfune
  1. T. Shinada, Regio- and Stereoselective Functionalization of Acyclic Terpenes, International Conference of Natural Products Biosynthesis(ICNPB), 17-23 July 2012, Awaji Yumebitai, Japan.
  2. T. Kotaki, T. Shinada, K. Kaihara, H. Numata, and Y. Ohfune, Biological Activity ofJjuvenile Hormone III Skipped Bisepoxide (JHSB3 in the Stink Bug, Plautia stali, 24th International Congress of Entomology), 19-25 August 2012, Deagu, Korea.
  3. T. Shinada, K. Kaihara1, T. Kotaki, H. Numata, Y. Ohfune, Structure Activity Relationship of a Novel Juvenile Hormone, JHSB3, 24th International Congress of Entomology, 19-25 August 2012, Deagu, Korea.
  4. T Shinada, Y. Yasuno, M. Hamada, Y. Ohfune, Development of Selective Ionotropic Glutamate Receptor Binding Antagonist: Structure-activity Relathionship Study of Kaitocephalin, “The 1st International Symposium on Chemical Biology of Natural products: Target ID and Regulation of Bioactivity”, 30 October – 1 November 2012, Kyoto, Japan.
  5. K. Maeda, T. Shinada, Y. Ohfune, Synthesis of Novel Peptide Analog by Iterative Linkage of Squaric Acid-Containing Amino Acid, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster).
  6. A. Manabe, T. Shinada, Y. Ohfune, Synthetic Study of Tetrodotoxin, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster)
  7. K. Sakaguchi, W. Akagi, N. Ikeda, M. Higashino, T. Shinada, Y. Ohfune, Chirality-Transferring Cationic Intramolecular Cyclization Reaction ofα-Siloxysilanes, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster)
  8. A. Shimoda, T. Okada, T. Shinada, K. Sakaguchi, Y. Ohfune, Au-Catalyzed Cyclization of 1-Arylbut-3-yn-1-ols to Substituted Naphthalenes, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster)
  9. Y. Wakabayashi, K. Shimamoto, T. Shinada, Y. Ohfune, Synthesis of Diaminopimelic Acid Derivatives and Their Biological Activity, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster)
  10. Y. Yasuno, T. Shinada, Y. Ohfune, Synthetic Study of Phomopsin A, the Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12), 12-16 November 2012, Kyoto, Japan (poster)
Hidenori Watanabe
Professor,Graduate School of Agricultural and Life Sciences, The University of Tokyo
  1. Hidenori Watanabe, Yuichi Fukatsu and Tetsuji Murase, “Synthetic Studies on Structurally Unique Natural Products” in The 7th International Conference on Cutting-Edge Organic Chemistry in Asia, Singapore (Dec, 2012).
Kosuke Namba
Associate Professor, Hokkaido University /
Professor, Graduate School of Pharmaceutical Science The University of Tokushima
Satoshi Ichikawa 
Associate Professor,  Faculty of Pharmaceutical Science, Hokkaido University
Haruhiko Fuwa
Associate Professor, Graduate School of Life Sciences, Tohoku University
Hideyuki Shigemori 
Professor, Graduate School of Life and Environmental Sciences, University of Tsukuba
  1. Kosumi Yamada, Nudtanicha Chaithongsri, Riffat Jabeen, Tsuyoshi Hasegawa, Koji Hasegawa, Hideyuki Shigemori, “New Insights on Mechanism of Blue-light Induced Growth Suppression in Maize Shoot”, Auxin 2012, Hawaii, USA (Dec. 2012)
Hirokazu Kawagishi 
Professor, Research Institute of Green Science and Technology, Shizuoka University
  1. Hirokazu Kawagishi, “Anti-dementia Compounds from the mushroom Hericium erinaceum”, The 18th Congress of the International Society for Mushroom Science, Beijing, China, (Aug, 2012)
  2. Hirokazu Kawagishi, “The angel’s wing mystery -Attempt to disclose the molecular mechanism of acute encephalopathy caused by eating angel’s wing oyster mushroom (Sugihiratake) -”, International Symposium on Natural Products Chemistry and Chemical Biology 2012, Hangzhou, China, (Nov, 2012)
Makoto Ojika
Professor, Graduate School of Bioagricultural Sciences, Nagoya University
  1. Makoto Ojika, Risa Yamada, Masatoshi Haga, Takayoshi Mamiya, Toshitaka Nabeshima, “Neurotrophic steroid glycosides from a starfish: in vivo activity and SAR-based synthesis of active analogs”, The 1st international symposium on chemical biology of natural products: target ID and regulation of bioactivity, Kyoto (Sep/Oct, 2012).
Shinichi Nishimura
Assistant Professor, Graduate School of Phramtical Sciences, Kyoto University
Katsunori Tanaka
Associate Chief Scientist, RIKEN
Co-Researcher: Takayuki Iwata, Masataka Kitadani.
  1. Yoshiyuki Manabe, Masahiro Nagasaki, Naoya Minamoto, Regina Salmasan, Katsunori Tanaka, Koichi Fukase,“Library-oriented Synthetic Study of N-Glycans” ACP2012、JSPS ICCEOCA-7/NICCEOCA-3、School of Biological Sciences, Nanyang Technological University、2012.12.13(Shingapore)
  2. Katsunori Tanaka,“Development of Smooth 6π-Azaelectrocyclization for Alkaloid Synthesis and Biomolecular Imaging & Engineering”, ACP2012、JSPS ICCEOCA-7 / NICCEOCA-3 、School of Biological Sciences, Nanyang Technological University、2012.12.13(Shingapore)
  3. Katsunori Tanaka,“Chemical Labeling and In Vivo Imaging of Biomolecules: Synthetic Approach toward Clinical Applications”, The 3rd International Scientific and Practical Conference Postgenomic methods of analysis in biology, and laboratory and clinical medicine, 2012.11.22(Kuzan Rossiya)
  4. Katsunori Tanaka,“Synthetic Chemist’s challenges to complex biomolecular systems”, 2nd RIKEN-KFU WORKSHOP, Physics, Chemistry and Biology of Complex Systems-On the way to trans disciplinary research、2012.11.20(Kuzan Rossiya)
  5. Yosuke Uchinashi, Katsunori Tanaka,Koichi Fukase,“Practical Microfluidic Procedures for a(alpha)-Sialylation”,The Twelfth International Kyoto Conference on New Aspects of Organic Chemistry(IKCOC-12)、2012.11.14(Kyoto)
  6. Yoshiyuki Manabe, Masahiro Nagasaki, Naoya Minamoto, Regina Salmasan, Katsunori Tanaka, Koichi Fukase,“Library Oriented Synthetic Study of N-Glycans”, The Twelfth International Kyoto Conference on New Aspects of Organic Chemistry(IKCOC-12), 2012.11.13(Kyoto)
  7. T. Iwata, Katsunori Tanaka, S. Shirotsuki, C. Kageyama, T. Tahara, S. Nozaki, E. R. O. Siwu, S. Tamura, S. Douke, N. Murakami, H. Onoe, Y. Watanabe, K. Fukase, “Regulation of In Vivo Protein / Protein Interaction by Template-Assisted Synthesis”, The first International Symposium on Chemical Biology of Natural Products Target ID and Regulation of Bioactivity, 2012.10.31~2012.11.01 (Kyoto)
  8. Katsunori Tanaka, “Renaissance of Traditional Transformations Under Microfluidic Conditions: Practical Synthesis of Biofunctional Natural Products”, Flow Chemistry Asia、Select Biosciences Ltd., 2012.10.26(Shingapore)
  9. Katsunori Tanaka, “A New Strategy of Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6p-Azaelectrocyclization”, Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University、Host: Prof. Shunsuke Chiba、 2012.10.24(Shingapore)
  10. Katsunori Tanaka, “A Synthetic Chemist’s Approach to Chemical Biology: From Enzyme Inhibition, Natural Products Synthesis to In Vivo Imaging by 6p-Azaelectrocyclization”, Hong Kong University of Science and Technology, Dept of Chemistry、Host: Prof. Zhi-hong GUO, 2012.10.5(Hong Kong)
  11. Katsunori Tanaka, “A Synthetic Chemist’s Approach to Chemical Biology: From Enzyme Inhibition, Natural Products Synthesis to In Vivo Imaging by 6p-Azaelectrocyclization”, Chinese University of Hong Kong Dept of Chemistry、Host: Prof. Jiang XIA、2012.10.4(Hong Kong)
  12. Katsunori Tanaka, “A Synthetic Chemist’s Approach to Chemical Biology: From Enzyme Inhibition, Natural Products Synthesis to In Vivo Imaging by 6p-Azaelectrocyclization”, University of Hong Kong Dept of Chemistry、Host: Prof. Pauline Chiu、2012.10.3(Hong Kong)
  13. Katsunori Tanaka, “A Synthetic Chemist’s Approach to Chemical Biology: From Enzyme Inhibition, Natural Products Synthesis to In Vivo Imaging by 6p-Azaelectrocyclization”, Hong Kong Polytechnic University, Dept of Applied Biology and Chemistry、Host: Prof. Man-kin Wong、2012.10.3(Hong Kong)
  14. K.Fukase, Katsunori Tanaka, Y.Fujimoto, Y.Uchinashi, A .Shimoyama, “Microfluidic glycosylation and application to biofunctional glycans”, 26th International Carbohydrate Symposium、International Carbohydrate Organization、2012.7.24(Madrid)
  15. Katsunori Tanaka, K.Moriwaki, T.Nakagawa, S.Yokoi, K.Koyama, E.Miyoshi, K.Fukase, “Noninvasive imaging of glycan-dependent tumor metastasis through live cell labeling by azaelectrocyclization”, 26th International Carbohydrate Symposium、International Carbohydrate Organization、2012.7.24(Madrid)
  16. Ambara Pradipta, Katsunori Tanaka, “Reaction Based Approach of Novel Post-Translational Modification”, The Second Asian Chemical Biology Conference、The Forum on Biomolecular Chemistry, 2012.7.4-6(Okinawa)
  17. Regina Salmasan, Masahiro Nagasaki, Yoshiyuki Manabe, Katsunori Tanaka, Koichi Fukase, “Solid Supported Synthesis of N-Glycans: N-Glycosylation and Cleavage”, The Second Asian Chemical Biology Conference、The Forum on Biomolecular Chemistry, 2012.7.4-6(Okinawa)
Kazunobu Toshima
Professor, Faculty of Science and Technology, Keio University
  1. Kazunobu Toshima, Yusuke Aoki, Daisuke Takahashi, “Photodegradation of drug-resistant influenza virus neuraminidase using designed anthraquinone-sialic acid hybrids”, The 12th International Kyoto Conference on New Aspects of Organic Chemistry, Rihga Royal Hotel KYOTO, Kyoto, Nov. 12-16, 2012.
  2. Kazunobu Toshima, “Light-activable and molecular-targeted (LAMTA) molecules for control of biomacromolecule functions”, The 1st International Symposium on Chemical Biology of Natural Products : Target ID and Regulation of Bioactivity, Kyoto Century Hotel, Kyoto, Oct. 31- Nov.1, 2012.
  3. Kazunobu Toshima, “Target-selective photodegradation of glycolipid LPS and inhibition of macrophage activation by designed anthraquinone-boronic acid hybrids”, 8th Keio LCC – Yonsei CBMH Joint Symposium 2012, Sapporo, Hokkaido, Oct. 26-27, 2012.
  4. Kazunobu Toshima, “Photodegradation of glycolipid LPS and inhibition of macrophage activation using designed anthraquinone-boronic acid hybrids”, 17th Malaysian Chemical Congress 2012, Putra World Trade Centre, Kuala Lumpur, Malaysia, Oct. 15-17, 2012.
  5. Daisuke Takahashi, Takuya Miura, Kazunobu Toshima, “Photodegradation of target glycolipid LPS and inhibition of macrophage activation by anthraquinone-boronic acid hybrids”, 26 International Carbohydrate Symposium, Madrid, Spain, July 22-27, 2012.
  6. Shuho Tanimoto, Daisuke Takahashi, Kazunobu Toshima, “Target-selective photo-degradation of HIV-1 protease and inhibition of HIV-1 replication in living cells by a fullerene-sugar hybrid”, 26 International Carbohydrate Symposium, Madrid, Spain, July 22-27, 2012.
Yoko Saikawa
Lecture, Faculty of Science and Technology, Keio University
  1. Yoko Saikawa, “Studies on the natural ligands responsible for non-allergic sneeze reflex”The 1st International Symposium oh Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
    (Kyoto)2012 Oct 31th.
Seijiro Hosokawa
Professor, Faculry of Science and Engineering, Waseda University
Co-Researcher:Mayumi Okamoto, Isao Shimizu.
  1. Seijiro Hosokawa, “Total Synthesis of Natural Products Possessing the Substituted Quinone and Multiple Stereogenic Centeres”, BIT’s 3rd Annual International Conference of Medichem-2012, Beiging (May, 2012).
  2. Mayumi Okamoto, Isao Shimizu, “Synthetic Estradiol Bioprobes and Their Application”, 15th International Congress on Hormonal Steroids and Hormones & Cancer, Kanazawa, Japan (Nov, 2012).
  3. Mayumi Okamoto, Isao Shimizu, “Synthetic Steroid Bioprobes and Their Application”, 3rd Anniversary Symposium of Waseda Bioscience Research Institute in Singapore, Singapore, (Nov, 2012).
Go Hirai
Senior Research Scientist, RIKEN
  1. G. Hirai, M. Kato, K. Oonuma, E. Nishizawa, T. Miyagi, and M. Sodeoka, “Sialidase-resistant Ganglioside GM3 Analogues”, RIKEN-MAX PLANCK JOINT RESEARCH CENTER Kick Off Symposium, Dortmund, Germany (Mar, 2012).
  2. F. Thuaud, G. Hirai, T. Cruchter, A. Ito, M. Yoshida, M. Sodeoka, “Synthetic Studies of Spectomycins, Protein SUMOylation Inhibitors”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto, Japan (Oct. 2012).
  3. G. Hirai, “Synthesis of Natural Product Derivatives Which Control the Post-translational Modifications of Proteins”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto, Japan (Oct. 2012).

【A03】

Minoru Ueda, A03 Group Leader
Professor, Graduate School of Science, Tohoku University
  1. Minoru Ueda, Chemical Biology of Glycoside Natural Products, The Second Asian Chemical Biology Conference (ACBC2), Okinawa, Japan (Jul 4-6, 2012).
  2. Minoru Ueda, Chemical Biology of Naturally Occurring Glycosides: “Glycosylation Switching”, The International Symposium on Chemical Biology of Natural Products, Kyoto, Japan (Oct 31-Nov 1, 2012).
  3. Minoru Ueda, “Glycosylation Switching”: Glycosylation regulates mode-of-action of bioactive natural products, 3rd International Symposium on Creation of Functional Materials-Life Science and Materials-, Tsukuba, Japan (Dec 10-11, 2012).
Naoki Kanoh
Associate Professor, Graduate School of Pharmaceutical Sciences, Tohoku University
  1. Naoki Kanoh, “Dual Structure-Activity Relationship of a Naturally-occurring Osteoclastogenesis Inhibitor Methyl Gerfelin”, in Cambodian Malaysian Chemical Congress 2012, Siem Reap, Cambodia (October, 2012).
  2. Naoki Kanoh, “Synthesis and Structure-Activity Relationship of Vicenistatin, aNaturally-occurring 20-Membered Macrolactam Glycoside,”, in Malaysian Chemical Congress 2012, Kuala Lumpur, Malaysia (October, 2012).
Hideo Kigoshi
Professor, Faculty of Pure and Applied Sciences, University of Tsukuba
Co-Researcher: Ichiro Hayakawa
  1. Hideo Kigoshi, “Total Synthesis of 13-Oxyingenol”, 13th International Symposium on Natural Product Chemistry (ISNPC-13), Karachi, Pakistan (Sep, 2012).
  2. Hideo Kigoshi, “Total Synthesis of 13-Oxyingenol”, The 2012 International Symposium on Natural Products Chemistry and Chemical Biology, Hangzhou, China (Nov, 2012).
Toshio Nishikawa
Professor, Graduate School of Bioagricultural Sciences, Nagoya University
Co-Researcher :Masaatsu Adachi,Keiichi Konoki.
  1. Toshio Nishikawa “Synthesis of Guanidine-Containing Natural Products”, International Symposium on Natural Products Chemistry and Chemical Biology 2012 , Hangzhou, China, (Nov, 2012).
  2. Toshio Nishikawa, Masaatsu Adachi, Ryo Sakakibara, Shouta Tokoro, Takuya Imazu, Yoshiki Satake, Minoru Isobe “Collective Synthesis of Tetrodotoxin and its Analogus”, The 7th International Conference on Cutting-Edge Organic Chemistry in Asia and The 3rd New Phase International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-7/NICCEOCA-3), Singapore, (Dec 2012).
Makoto Sasaki
Professor Graduate School of Life Sciences, Tohoku University
Co-Researcher Haruhiko Fuwa, Keiichi Konoki
Fumi Nagatsugi
Professor, The Institute of Multidisciplinary Research for Advanced Materials, Tohoku University
  1. Yuki Ishizawa, Kaname Sasaki, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi, Synthesis of Peptide Nucleic Acid (PNA) Incorporating 4-Amino-6-Oxo-2-Vinylpyrimidine (AOVP) (The 39th International Symposium on Nucleic Acid Chemistry, 2012/11/15-17, Nagoya University, Nagoya)
  2. Shinya Hagihara, Yuta Ida, Nao Iwamoto, Shuhei Kusano, Fumi Nagatsugi, Development of Crosslink Forming Oligonuleotides for Intracellular Gene Regulation (The 39th International Symposium on Nucleic Acid Chemistry, 2012/11/15-17, Nagoya University, Nagoya)
  3. Shuhei Kusano, Shinya Hagihara and Fumi Nagatsugi, Development of the Acyclic Pyrimidine Derivative for Selective Cross-linking Reaction to 8-Oxoguanine (The 39th International Symposium on Nucleic Acid Chemistry, 2012/11/15-17, Nagoya University, Nagoya)
  4. Fumi Nagatsugi, Development of the Molecular Probes Targeted for Gene (The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, 2012/10/31-11/1, Kyoto Century Hotel, Kyoto )
  5. Takuma Moki, Kaname Sasaki, Fumi Nagatsugi, Investigation of the Strategy to Selective Chemical Modification for the Nucleobase Opposite the Abasic site (Tohoku University Campus Asia Program Summer School 2012, 2012/8/20-23, Tohoku University, Sendai)
  6. Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi, Development of the Intracellular Control of Gene Expression Using Selective Crosslinking Reactions (Tohoku University Campus Asia Program Summer School 2012, 2012/8/20-23, Tohoku University, Sendai)
  7. Yuki Ishizawa, Kaname Sasaki, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi, Synthesis of Peptide Nucleic Acid (PNA) Incorporating 4-Amino-6-Oxo-2-Vinylpyrimidine (Tohoku University Campus Asia Program Summer School 2012, 2012/8/20-23,Tohoku University, Sendai)
  8. Shinya Hagihara, Shuhei Kusano, Nao Iwamoto, Fumi Nagatsugi, Crosslink Forming Oligonucleotide as a Steric Terminator of Translation(20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, 2012/8/5-9 Montreal, Canada)
  9. Fumi Nagatsugi, Yusuke Takahashi, Maiko Kobayashi and Shunsuke Kuwahara, Synthesis of the Light-Driven Molecular Motors Conjugated with Peptide and Evaluation of the DNA Binding Properties (20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, 2012/8/5-9 Montreal, Canada)
  10. Shuhei Kusano, Shinya Hagihara, Takuma Moki and Fumi Nagatsugi, Developement of the Acyclic Pyrimidine Derivative for Selective Cross-linking Reaction to Guanine (20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, 2012/8/5-9 Montreal, Canada)
  11. Yuki Ishizawa, Kaname Sasaki, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi, Revisiting the Interstrand Cross-linking Reaction: PNAs to Oligonulcleotides (The second Asian Chemical Biology Conference ACBC 2012, 2012/7/4-6, Southern Beach Hotel&Resort Itoman, Okinawa, Japan)
Takamitsu Hosoya
Pofessor, Institute of Biomaterials and Bioengineering Tokyo Medical and Dental University
  1. Takamitsu Hosoya, Suguru Yoshida, Akira Shiraishi, Kimiyuki Kanno,
    Takeshi Matsushita, Kohei Johmoto, Hidehiro Uekusa, The Twelfth International Kyoto Conference on New Aspect of Organic Chemistry (IKCOC-12),Enhanced Clickability of Doubly Sterically-Hindered Aryl Azides,(2012/11/15)Kyoto
  2. Takamitsu Hosoya, The first official conference of the International Chemical Biology Society(ICBS2012),Azido-type selective reactions promoting chemical biology (2012/10/4), Boston
Yousuke Takaoka
Assistant Professor, Graduate School of Engineering, Kyoto University
  1. Yousuke Takaoka, Itaru Hamachi, “Quantitative Comparison of Protein Dynamics in Live Cells and in vitro by In-Cell 19F-NMR in International Joint Symposium on Single-Cell Analysis 2012, Kyoto Research Park, Japan (Nov, 2012).
Junko Ohkanda
Associate professor, Institute for Chemical Research, Kyoto University
  1. J. Ohkanda, M. Tsubamoto, N. Kato, “Toward selective inactivation of K-Ras: Bivalent dual inhibitors for disrupting protein-protein interactions of protein prenyltransferases”, 16th SANKEN International Symposium 2013, Osaka University, Osaka (Jan. 22-23, 2012).
  2. J. Ohkanda, “Natural product-based chemical probes for detecting 14-3-3-phospholigand interactions”, G3 Alliance Meeting, Tokyo Institute of Technology, Tokyo (Oct. 12, 2012).
  3. J. Ohkanda, “Assembling small molecules for disrupting and detecting protein-protein interactions”, Department of Pharmaceutical Sciences of College of Pharmacy, University of South Florida, USA (Oct. 8, 2012).
  4. J. Ohkanda, “Natural product-based chemical probes for detecting 14-3-3-phospholigand interactions”, The Sixth Peptide Engineering Meeting PEM6, Emory University, USA (Oct. 4, 2012).
  5. J. Ohkanda, “Fusicoccin-based fluorescent probes for detecting 14-3-3 interactions with phosphorylated ligands”, 2012 Asian Chemical Biology Conference ACBC2012, Okinawa, (2012 July 4 to 6, 2012).
  6. J. Ohkanda“Assembling small molecules for disrupting and detecting protein-protein interactions”, Department of Chemistry, University of Minnesota, Minneapolis, USA (June 7, 2012).
  7. J. Ohkanda, “Assembling small molecules for disrupting and detecting protein-protein interactions”, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, USA (2012 June 5).
  8. J. Ohkanda, M. Takahashi, N. Kato, T. Nishi, I. Hamachi, M. Noda, S. Uchiyama, “Toward detecting protein-protein interactions by a chemical probe: fusicoccin analogs for ligand-dependent 14-3-3 labeling”, The 15th SANKEN International Symposium 2012, Osaka University, Osaka (Jan. 12-13, 2012).
Misako Aida
Professor, Graduate School of Science, Hiroshima University
Akira Otaka
Professor, Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences,
The University of Tokushima
  1. A. Otaka. Chemical Protein Synthesis Using N-Sulfanylethylanilide PeptideThe 14rd Akabori Conference, Niseko, Japan (2012)
  2. A. Otaka. N-Sulfanylethylanilides as a Versatile Chemical Device for the Protein Chemistry 2012 SNU symposium on Medicinal Chemistry, Seoul, Korea (2012)
Hideo Takahashi
Professor, Graduate School of Medical Life Science, Yokohama City University
  1. Hideo Takahashi, “NMR approach for ligand-based drug discovery: DIRECTION approach for the pharmacophore mapping of drug candidates”, The 3rd International Symposium on Drug Discovery and Design by NMR, Yokohama (Oct, 2012)
Toshiyuki Kan
Professor, School of Pharmaceutical Sciences, University of Shizuoka
  1. Toshiyuki Kan “Synthetic Study on Heterocyclic Natural Products” Japan-Singapore Bilateral Symposium on Synthetic Organic Chemistry (Nanyang) Oct 30 2012.
Hiroyuki Nakamura
Professor, Gakushuin Iniversity / Tokyo Institute of Technology
  1. H. Koganei, S. Tachikawa, M. Suzuki, K. Ono, H. Nakamura, Antitumor Activity of Boron Lipid Liposomes with Neutron Irradiation, SIMS2012,(Tsukuba), March 17th-19th 2012.
  2. H. Nakamura, Dodecaborate Lipid Liposomes as New Vehicles for Boron Delivery System of Neutron Capture Therapy, The 13th Boron In The Americas Conference(USA), June 3rd-6th 2012.
  3. H. Nakamura, Carboranylphenoxyacetanilides as HIF-1 Inhibitors:Photoaffinity Probe Design for Identification of Heat Shock Protein 60, a Primary Target, A celebration of Organic Chemistry(Invited) (UK), June 15th 2012.
  4. H. Nakamura, Boron-Based Drug Design: From Chemical Biology to Neutron Capture Therapy, Paris Tech Seminar,(Invited) (France), June 18th 2012.
  5. M. Bialek-Pietras, A. B. Olejniczak, S. Tachikawa, H. Nakamura, Z. J. Lesnikowski, Cholesterol-boron cluster conjugates:Synthesis via dioxane ring opening of the oxonium derivative of the boron cluster and preliminary physicochemical and biological evaluation, 4th Congress of the European Association for Chemical and Molecular Sciences Prague(Czech Republic), August 26th -30th 2012.
  6. F. Yoshida, K. Nakei, T. Yamamoto, M. Shirakawa, H. Nakamura, Pretreatment with buthionine sulfoximine enhanced uptake and retention of BSH for BNCT, Alexander Zaboronok, Akira Matsumura,15th International congress on Neutron Capture Therapy(Tsukuba), September 10th -14th 2012.
  7. H. Nakamura, T. Miyoshi, S. Tachikawa, H. Koganei, S. Kojima, M. Suzuki, K. Ono, closo-Dodecaborate-conjugated cholesterols:Synthesis and click imaging of their liposomesin cells, 15th International congress on Neutron Capture Therapy(Tsukuba), September 10th -14th 2012.
  8. S. Tachikawa, T. Miyoshi, H. Koganei, D. Kanoh, H. Ban, M. Suzuki, M. Kirrihara, K. Ono, H. Nakamura, Development of liposomal boron agents for neutron capture therapy, 15th International congress on Neutron Capture Therapy(Tsukuba), September 10th -14th 2012.
  9. H. Nakamura, Development of inhibitors targeting hypoxia cell signaling, 2th COLLOQUE FRANCO-ROUMAIN DE CHIMIE MEDICINALE, Invited (Iasi, Rumania)October 3rd-5th 2012
  10. H. Nakamura, Boron-Based Drug Design: From Chemical Biology to Neutron Capture Therapy, the Institute of Medical Biology (IMB) Poland Academy of Science, Seminar、Invited、(Lotz, Poland)、October 9th 2012
  11. H. Nakamura, Discovery of HIF-1a Degradation Induced by Inhibition of HSP60 under Hypoxia, 1st International Symposium on Chemical Biology of Natural Products:Target ID and Regulation of Bioactivity, (Kyoto), Ocotober 31st 2012
  12. H. Minegishi, S. Fukashiro, H. S. Ban, H. Nakamura, Discovery of Indenopyrazoles as HIF-1α Inhibitors, 12th International Kyoto Congress of Organich Chemistry (IKCOC-12) , (Kyoto), November 12nd-16th 2012
  13. T. Matsukawa, L. Tazaki, H. S. Ban, H. Nakamura, Diphenylcarboranes as a new class of hypoxia inducible factor inhibitors, 12th International Kyoto Congress of Organich Chemistry(IKCOC-12), (Kyoto), November 12nd-16th 2012
  14. Tsuyuka Sugiishi, Hiroyuki Nakamura, CH vs CC Bond Activation of Propargylic Amines in the Presence of Pd, Cu or Zn Catalysts, 12th International Kyoto Congress of Organich Chemistry(IKCOC-12) , (Kyoto), November 12nd-16th 2012
  15. H. Nakamura, closo-Dodecaborate-conjugated cholesterols: Synthesis and click imaging of their liposomes in cells, Trilaterla Meeting of BNCT in Taipei, (Taiwan), December 1st 2012
  16. H. Nakamura, Boron-Based Drug Design: Discovery of HIF-1α Degradation Induced by Inhibition of HSP60 under Hypoxia, Korea University, Seminar, Invited Daejon (South Korea) December 28th
Nobuyuki Kanzawa
Associate Professor, Faculty of Science and Technology, Sophia University
  1. S. Hamaguchi, Y. Otsuka N. Kanzawa, “Localization analysis of MetE, a receptor for the Leaf-Opening Factor of the genus Cassia”, 2012 Annual Meeting of the American Society for Cell Biology, San Francisco, CA, USA (Dec 15-19, 2012)
  2. H. Ohsugi, J. Hatsukawa, Y. Otsuka, M. Aizawa, N. Kanzawa, “Establishment of a real-time evaluation system of the osteoconduction using fluorescent proteins”, 2012 Annual Meeting of the American Society for Cell Biology, San Francisco, CA, USA (Dec 15-19, 2012)
Yu Nakagawa
Senior Research Scientist, RIKEN
  1. Yu Nakagawa, “Identification of the target glycan of Pradimicins, small natural products with C-type lectin-like properties”, The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto (Oct, 2012).
Makoto Muroi
Senior Research Scientist, RIKEN
  1. M. Muroi and H. Osada “Proteome-based profiling approach to predict targets of bioactive small molecules using two-dimensional fluorescence differential gel electrophoresis (2D-DIGE) ” The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity, Kyoto, Japan, 2012 Oct 31-Nov 1.

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