Chemical Biology of Natural Products: Target ID and Activity Control - Scientific Research on Innovative Areas, a MEXT Grant-in-Aid Project FY2011-2015

Our mission

The goals of this research project are as follows: 1) to develop a versatile methodology for identifying the target(s) of biologically active natural products (or naturally occurring ligands,“NOLs”; 2) to establish a rational molecular approach to designing a simplified NOL (such as “Halaven”) based on the structure of the ligand/target complex; and 3) to generate new concepts relating to the control of bioactivity that depend on the “master key” characteristics of natural NOLs, for instance, the idea that a living organism selects the precise “master key” bioactivity appropriate for each situation in vivo.

Introduction

EVENTS

2014-10-31 Event Molecular Function of Natural Products: Advances towards Chemical Biology
2014-06-09 Event The 3rd International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
2013-04-11 Event The 2nd International Symposium on Chemical Biology of Natural Products:Target ID and Regulation of Bioactivity
2012-11-07 Event The photograph of "The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity."
2012-05-04 Event The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity

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NEWS

2012-06-23 News A “Concept Review” article is released in Chemistry Letters as an open access article.
2012-02-12 News Website newly launched.

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